Isuku ryinshi Ethyl 4-bromobutyrate CAS No 2969-81-5 hamwe nigiciro cyiza

Mu icupa rya reaction ryashyizwemo na stirrer, therometero na trube ya vent, 200 g (2,33 mol) ya γ -butyrolactone na 375mL ya etanol ya anhydrous yongewemo, ikonjeshwa kugeza kuri 0 ℃ mu bwogero bwumunyu wa barafu, hanyuma gaze ya hydrogène bromide yumye kugeza itangijwe kugeza reaction zagumye zidahindutse, byatwaye amasaha agera kuri 2.Kurekera kuri 0 ℃ kuri 24h.Suka reaction mu mazi akonje ya 1L, ubyuke neza, utandukanye urwego kama, hanyuma ukuremo amazi hamwe na bromoethane kabiri, 10mL buri mwanya.Gukomatanya ibice kama, koza Ethanol hamwe na 2% yumuti wa potasiyumu hydroxide, kuvanga aside hydrochloric namazi, kumisha hamwe na sodium sulfate ya anhydrous, kugarura ibishishwa, gucamo ibice, no gukusanya uduce duto kuri 97 ~ 99 ℃ / 3.3 kPa kugirango ubone 350 ~ 380 g ya Ethyl γ-bromobutyrate (1) n'umusaruro wa 77% ~ 84%.